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You are here: Home / Dynamic Vapor Sorption (DVS) Analysis / DVS accessories and options / Combination of DVS with Raman Spectroscopy
DVS Raman spectroscopy combination

Combination of DVS with Raman Spectroscopy

Sensor fusion combining water vapor sorption with Raman spectroscopy is the most sophisticated option for the installation of additional sensors to the ProUmid SPS vapor sorption analyzer. The DVS-Raman spectroscopy combination is a powerful tool to monitor structural changes as polymporphic conversion of materials.

Some examples for usage of Raman in combination with moisture sorption are:

  • Crystallinity
  • Polymorphic forms
  • Phase transitions
  • Contaminant identification
  • Raw material verification
  • Blend uniformity
  • API concentration

All SPS instruments can be equipped or retrofitted to integrate a PhAT Probe for the Kaiser RamanRxn1 Analyzer. The main benefits of the PhAT Probe for Raman analysis of solids are the representative mm-scale analysis and reproducible sampling.

Software integration

The Raman spectrometer is triggered via the SPS software. A menu allows to select from which samples Raman spectra shall be acquired and when. Events for triggering the acquisition can be the avievement of the equlibrium state or a fixed time interval. All sample-specific data are transferred to the Raman software HoloPro®.

The possibility to evaluate the sorption isotherms with corresponding Raman spectra plus the possibility to compare and measure multiple samples at the same time opens new and exciting perspectives for the analysis of solid samples.

Contact us for more information on the Raman Spectrometer option for the SPS

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    Water Vapour Sorption Analyzer SPS
    SPS11-10µSPSx-1µ High LoadSPSx-1µ AdvanceSPS23-100n

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    Vsorp BasicVsorp PlusVsorp Enhanced

    Sorption Accessories
    Option Camera
    Option Raman Spectroscopy
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    21 CFR Part 11 compliant software package
    Reference Material for Humidity Validation

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    MHG32MHG100

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      Contract Analysis: Dynamic Vapor Sorption (DVS)
      Sorptions Isotherm, Sorptions KineticsPermeability, Water Vapor Transmission Rate (WVTR) of foils or packaging materials

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        Please send me a quotation for

        item no. Description quantity package size
        100913 sample dishes 18 mm box (100 pieces)
        100914 sample dishes 33 mm box (100 pieces)
        100486 sample dishes 50 mm box (100 pieces)
        100916 sample dishes 86 mm box (100 pieces)
        100917 distance pieces set (12 pieces)
        101867 mesh cover 50 mm set (12 pieces)
        101596 PTFE inserts set (12 pieces)
        100485 secondary sample dishes 38 mm box (10 pieces)
        100910 sample carousel 5 sample positions piece
        100908 sample carousel 11 sample positions piece
        100909 sample carousel 23 sample positions piece

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              Please send me the following Application Note / White paper

              Application Notes

              Food

              AN_20-01 Amorphous lactose in food
              AN_20-02 Amorphous fractions in sucrose and sucrose containing model food systems
              AN_20-03 Deliquescence and deliquescence lowering of food ingredients and blends
              AN_20-04 Dehydration behavior of bread crumb and crust

              Pharma

              AN_20-05 Amorphous lactose in the pharmaceutical industry
              AN_20-06 Hydrate formation of L-lysine HCl
              AN_20-09 Hydrate formation of creatine

              Building materials

              AN_20-07 Water vapor sorption of plaster

              Permeability of Packaging material and Foils

              AN_12-01 Water vapor permeability of films

              AN_15-01 Water vapor sorption of product packages

              White Papers

              Universal

              WP_20-01 Amorphous content lactose

              Food

              WP_20-02 Amorphous fractions in sucrose and sucrose containing model food systems
              WP_20-03 Deliquescence and deliquescence lowering of food ingredients and blends

              Pharma

              WP_20-06 Hydrate formation of L-lysine HCl

              * I have read and accepted the privacy policy.

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