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You are here: Home / Dynamic Vapor Sorption (DVS) Analysis / Applications for Dynamic Vapor Sorption / Pharmaceutical Industry Applications for DVS

Pharmaceutical Industry Applications for Dynamic Vapor Sorption

In the pharmaceutical industry, materials get into contact with water in many different ways, for example during manufacturing steps such as crystallization processes, spray drying or wet granulation. Also, during storage and transport, pharmaceutical raw materials or final products are typically exposed to an atmosphere containing water vapor, causing interactions between solids and water. In multi-component formulations, water may also migrate between moist and dry ingredients. With regard to the compaction behavior during tabletting, a certain moisture content is required to obtain satisfactory products. In general, however, the exposure to moisture causes undesirable product changes. Therefore, it is of utmost importance for the development of new drugs to have comprehensive and detailed information on water-solid interactions and the influence of moisture on the physicochemical properties of Active Pharmaceutical Ingredients (APIs) and excipients.

Applications

DVS Hydrate Formation in Pharmaceutical Industry
Hydrate Formation
DVS Determination of Amorphous Content in Pharmaceutical Industry
Amorphous Content

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    Contract Analysis: Dynamic Vapor Sorption (DVS)
    Sorptions Isotherm, Sorptions Kinetics
    Permeability, Water Vapor Transmission Rate (WVTR) of foils or packaging materials

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      Please send me a quotation for

      item no. Description quantity package size
      100913 sample dishes 18 mm box (100 pieces)
      100914 sample dishes33 mm box (100 pieces)
      100486 sample dishes50 mm box (100 pieces)
      100916 sample dishes86 mm box (100 pieces)
      100917 distance pieces set (12 pieces)
      101596 PTFE inserts set (12 pieces)
      100485 secondary sample dishes 38 mm box (10 pieces)
      100910 sample carousel 5 sample positions piece
      100908 sample carousel 11 sample positions piece
      100909 sample carousel 23 sample positions piece

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        Please send me the following Application Note / White paper

        Application Notes

        Food

        AN_20-01 Amorphous lactose in food
        AN_20-02 Amorphous fractions in sucrose and sucrose containing model food systems
        AN_20-03 Deliquescence and deliquescence lowering of food ingredients and blends
        AN_20-04 Dehydration behavior of bread crumb and crust

        Pharma

        AN_20-05 Amorphous lactose in the pharmaceutical industry
        AN_20-06 Hydrate formation of L-lysine HCl
        AN_20-09 Hydrate formation of creatine

        Building materials

        AN_20-07 Water vapor sorption of plaster

        Permeability of Packaging material and Foils

        AN_12-01 Water vapor permeability of films

        AN_15-01 Water vapor sorption of product packages

        White Papers

        Universal

        WP_20-01 Amorphous content lactose

        Food

        WP_20-02 Amorphous fractions in sucrose and sucrose containing model food systems
        WP_20-03 Deliquescence and deliquescence lowering of food ingredients and blends

        Pharma

        WP_20-06 Hydrate formation of L-lysine HCl

        * I have read and accepted the privacy policy.

        (* required fields)
        By clicking on the button "Submit", you are authorizing ProUmid GmbH & Co. KG to make use of the entered data in the contact form for contacting you so that we may answer your request and to provide you with information on the requested products and services. We will not pass your personal data to third parties. You will be able to unsubscribe from all of our e-mails at any time. Please have a look at our privacy policy for more information on how we use your data.